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Beyond brain imaging, attention has increasingly shifted toward peripheral tissues, where accessible biopsies such as skin samples provide a minimally invasive avenue to detect hallmark proteinopathies and extend biomarker discovery beyond the CNS

The data that support this study are also available from the corresponding authors upon request

215 Cyst(e)inase degrades extracellular cysteine and cystine and leads to decreased levels of intracellular cysteine and glutathione, which profoundly affects the redox potential of cancer cells 216 and counteracts the essential role of cysteine in cancer cells

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