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In situations characterized by inflammation, specific cytokines, notably TNF-, IL-6, and IL-1, amplify leptin production by acting as potent stimulants for adipocyte activity

49 , D394D403 (2021)

Oxidative stress plays a crucial role in the development of age-related diseases including arthritis, diabetes, dementia, cancer, atherosclerosis, vascular diseases, obesity, osteoporosis, and metabolic syndromes (Tan et al., 2015a