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does lidocaine use glutathione or glucuronidation Medicinal chemistry on metabolism(Phase I & Phase II Reactions) Chronic alcoholism lowers the Acetaminophen metabolism and NAPQI mediated mitochondrial effects Download Scientific Diagram Phase II Reactions Biotransformation of Drugs Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial
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