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Major hepatectomy in mouse First, 10% chloral hydrate was administered intraperitoneally

Safety Although the studies included in this review identified no important safety issues, orally administered l-carnitine supplementation has been linked to a increase in trimethylamine (TMA) and trimethylamine- N -oxide (TMAO), as unabsorbed carnitine is metabolised by the gut microbiota to TMA and later oxidised to TMAO in the liver

West PR, Amaral DG, Bais P, Smith AM, Egnash LA, Ross ME, Palmer JA, Fontaine BR, Conard KR, Corbett BA, Cezar GG, Donley ELR, Burrier RE

In conditiile in care oxigenul este in cantitati mici, se produc oxidari la nivelul celulelor si al tesuturilor