drug causes cysteine starvation glutathione depletion The versatile utility of as a target for cancer treatment Frontiers | System Xc−/GSH/GPX4 axis:
Frontiers System Xc GSH GPX4 axis: An important antioxidant system for the ferroptosis in drug resistant solid tumor therapy Cystine deprivation triggers CD36 mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells Cell Death & Disease Catabolism of extracellular glutathione supplies cysteine to support tumours Nature Glutathione metabolism in cancer progression and treatment resistance PMC
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