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Description

GPX4 plays a pivotal role in regulating lipid peroxides within cells and the reduction in GSH and GPX4 that we demonstrate in the IB3-1 AECs following FAC and erastin treatment is likely responsible for the increased lipid peroxidation that we found, as evidenced by the increase in MDA and C11-BODIPY

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It plays a vital role in protecting the developing fetus from oxidative stress and helps regulate cellular health throughout the pregnancy

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Am J Reprod Immunol

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T., Baker, M., Browne, W

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