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Then an optional step is to ask are non-ATSDR screening levels (like EPA RSLs or state guidelines) available in the site-specific medium

Additional investigations have examined its role in xenobiotic metabolism, heavy metal chelation, and immune cell function modulation

4 Materials and methods 4.1 Cell culture and in vivo experiments 4.1.1 Cell lines Four human NB cell lines were used in this paper: Be(2)-C (MNA), IMR5-/75-shMYCN (29) (MNA, doxycycline-inducible shRNA targeting MYCN, resulting in MYCN downregulation), IMR-32 (MNA), and SH-SY5Y/6TR(EU)/pTrex-Dest-30/MYCN (non-MNA, doxycycline-inducible transgene, resulting in MYCN overexpression)

It is important to follow the injection instructions provided by a healthcare provider or pharmacist, as well as any additional instructions that may be provided by the manufacturer of the specific B12 product being used