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The introduction of a single His residue into human GSH transferase A1-1 created an unprecedented enzymatic function, suggesting a strategy that may be of broad applicability in the design of new enzymes

NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis

aegypti populations tend to display higher genetic diversity, particularly in genes associated with immune function and ecological adaptation, compared with those in other parts of the world owing to a longer evolutionary history and larger ancestral populations [33]

Significantly, this process occurs independently of the adaptive immune system and is specific to the lung microenvironment