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Description

specifically in those lines with elevated OAS levels ( Figure 7A )

a corticosteroid, theophylline, and phosphodiesterase-4 (PDE4) inhibitor, either as a single therapy or together to reduce the severity of symptoms and recover the quality of life [1, 6], but there is doubt about the efficacy of these drugs [7]

Hector, A

In addition, mTORC1 promotes nucleotide synthesis by stimulating the mTHF cycle, which increases ATF4 levels to upregulate the expression of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) [45]

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