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Call your doctor for medical advice about side effects, or report them to the FDA at 1-800-FDA-1088

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Research has demonstrated that GHK-Cu treatment increases production of collagen (particularly type I and type III collagen, the predominant structural collagens in skin and connective tissues), glycosaminoglycans (including hyaluronic acid, which provides hydration, volume, and biochemical signaling in skin), decorin (a small proteoglycan involved in collagen fibril organization and growth factor regulation), and other matrix molecules critical for tissue structure and function

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By extracting aortic tissue from the mice and performing WB analysis, we found that the expression levels of P53 and FOXO4 were both elevated (Supplementary Figure S1A)

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