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doi: 10.3390/ijms20092297 108 RagelP.RaddatzN.LeidiE

The malate-aspartate shuttle (Borst cycle): how it started and developed into a major metabolic pathway

The first indications came from Gilchrest et al

CLINICAL TRIALS WITH CAGRILINTIDE Two clinical trials have investigated the efficacy of cagrilintide in comparison to the GLP-1 agonists liraglutide and semaglutide (Fig