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After confirming all entry criteria, the investigator or a designated team member will formally enroll the participant, obtaining written informed consent prior to any randomization or trial-related procedures

These findings highlight a connection between glycolysis and antioxidant defense and suggest that higher glycolytic activity of TrC1 AKT-E17K cells supports their antioxidant capacity, rendering the cells vulnerable to 2DG mediated inhibition of glycolysis and associated production of reduction equivalents and GSH

[DOI] [PMC free article] [PubMed] [Google Scholar] 275.Oliveira-Marques V

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