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From the first day of treatment, the animals weight, tumor volume, and overall health were monitored three times a week for 60 days

Ramsey SD, Holmes RS, Mcdermott CL, Blough DK, Petrin KL, Poole EM et al (2012) A comparison of approaches for association studies of polymorphisms and colorectal cancer risk

Conclusion: Taken together, these results suggest that oligodendrocyte dysfunction, driven by the intrinsic expression of mutant ATXN3 protein, may contribute to the pathophysiology of SCA3