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Description

PMID 30317438

It has been demonstrated that the ubiquitination of residues K322 and K366 via the K63 linkage of FSP1 and myristoylation of FSP1 facilitate the translocation of FSP1 to the plasma membrane [45, 47]

It decreases the lesion size of gastric ulcers induced by indomethacin (Cay-70270), aspirin (Cay-70260), or diclofenac (Cay-70680, Cay-22983) in rats at the same doses

Two strategies dominate: structural stabilization (modifications that resist proteases) on one side, and small non-peptide agonists that mimic a peptide's action without its fragility on the other