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In general, three components of the ghrelin system have been targeted in the search for an elusive pharmacological compound that will contribute to weight loss

Moreover, ferroptosis may not only play a direct role in AT, but also indirectly promote the development of obesity through the inflammatory response and insulin resistance caused by liver autonomic and immunomodulatory disorders( Figure 4 )

10.1073/pnas.1011379108 21 DilrubaS.KalaydaG

Yusuf et al., 2018) and cysteine modifications like oxidation or palmitoylation that contribute to a general aberration of cysteine residues proteostasis (Valle and Carr, 2017)