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Statistical analysis As the Bartlett test confirmed the homogeneity of variances for the dependent variables across different experiments, the results were analyzed collectively as a single experiment comprising six replicates

Thus, they demonstrated that Prx2 prevents metHb aggregation, and, probably acts as a chaperone for the denatured Hb [96]

[2] This may stimulate the production of second messengers like cAMP and IP3 (inositol trisphosphate), which could propagate the signal within the cell and possibly activate protein kinases that may phosphorylate target proteins and regulate cellular processes

After mating them with UBC-Cre ERT2/+ mice, TLK2 genes could be knocked out ubiquitously by tamoxifen (Sigma #T5648) via intraperitoneal injection in 75 mg/kg body weight once every 24 h for a total of 5 consecutive days