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Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study

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This loss of autophagy leads to an accumulation of ROS, which can exacerbate inflammation and eventually lead to carcinogenesis (Raju et al., 2012)

According to previous studies, certain inflammatory cytokines produced (in vitro) by the NF-B (Nuclear Factor kappa-light-chain-enhancer of activated B cells) signal pathways in response to external stimuli like lipopolysaccharide (LPS), which is enhanced during inflammation, include tumor necrosis factor (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1) [25]