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Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects

There was an increase in the serum concentration of vitamin D in participants who ingested the supplementation

Disclosures: Eleonora Scorletti: Nothing to Disclose, Helen Huang: Nothing to Disclose, David Zhang: Nothing to Disclose, Marijana Vujkovic: Nothing to Disclose, Joseph Park: Nothing to Disclose, Florian Kahles: Novo Nordisk, AstraZeneca, Bayer, Lilly, Sphingotec-14-4: Speaking and Teaching, Giorgio Sirugo: Nothing to Disclose, Michael Phillips: Nothing to Disclose, Kai Markus Schneider: Nothing to Disclose, Garret FitzGerald: Nothing to Disclose, Daniel Rader: Nothing to Disclose, Carolin Schneider: Nothing to Disclose 839 PLIN2 EXPRESSION IS A RELIABLE BIOMARKER OF MASH THAT IS SPECIFICALLY ASSOCIATED WITH INFLAMMATION AND BALLOONING RATHER THAN STEATOSIS Giulia Angelini 1 Sara Russo 1 Erminia Lembo 1 Ornella Verrastro 1 Caterina Guidone 1 Aldo TRYLESINSKI 2 Antonio Liguori 1 Sven Francque 3 Arun Sanyal 4 William Alazawi 5 Luca Miele 1 Geltrude Mingrone 1 , 1 Universit cattolica del sacro cuore, 2 Metadeq Diagnostic, 3 Antwerp University Hospital & University of Antwerp, 4 Virginia Commonwealth University, 5 Queen Mary University of London Background: Metabolic dysfunction-associated steatohepatitis (MASH) is the most common liver disease worldwide

Warning Food supplements should not be used as a substitute for a varied diet