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These animal models of kidney injury include diabetic kidney disease or diabetic nephropathy, renal ischemia-reperfusion injury, sepsis-induced kidney injury, unilateral ureteral obstruction (UUO)-induced kidney injury, cisplatin-induced kidney injury, cadmium-induced kidney injury, folic acid-induced kidney injury, and iron-induced acute kidney injury (Figure 1)

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In the course of this work he and Takeshi Kosaka, a Japanese-Chinese colleague, realised that the secretion of gastric acid was probably inhibited by a hormone in the blood released from the upper small intestine mucosa by the presence or digestion of fats

The reduction in the activity of GPx may predispose the body to accumulate hydrogen peroxide and lipid peroxides, as GPx activity reduces both hydrogen peroxide and lipid peroxides