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Are weaning infants at risk of iodine deficiency even in countries with established iodized salt programs

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1 Methylation is critical to a multitude of metabolic processes including: Cell division, DNA and RNA synthesis Detoxification and hormone biotransformation Neurotransmitter biosynthesis CNS development and neural tube formation Histamine clearance Phospholipid synthesis Myelination of peripheral nerves Methylation and Nutrient Status Particular attention has been focused on folate and MTHFR and other potential gene variants that influence folate metabolism and methylation

The applicant indicated that, while there may be cases where a second dose is needed, there is insufficient frequency to impact the reported weighted average of one dose per patient