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Although the CD4 + T cells is essential for clearance of infections, dysregulation may also lead to pathological conditions such as autoimmune diseases ( 3.2.1 Glutamine and thymus As the principal lymphoid organ, thymus is critical for the production and maturation of T cells ( 3.2.2 Glutamine and spleen The spleen, which combines the immune dynamic balance of the innate and acquired immune systems, is a vital organ and is primarily responsible for the immune surveillance of the blood ( + T-cell populations was maintained in mice pretreated with Gln in the sepsis group, and the expression of the antiapoptotic Bcl-2 gene was more pronounced and increased in splenic CD4 + T cells

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& Stevens, R