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435,436 Targeting lipid metabolism or signaling for disease therapeutics FAs are crucial for both health maintenance and disease development, and FA supplementation has emerged as an effective treatment method

[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Sedel F., Bernard D., Mock D.M., Tourbah A

In the small intestine, Paneth cells in the epithelial crypts produce antimicrobial peptides, including alpha-defensins and regenerating islet-derived 3-gamma, contributing to innate intestinal defence [40]