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In the plasma of patients with IPAH and the lung tissue of mice with hypoxia-PH, levels of the anti-inflammatory substance Resolvin E1 and its receptor, ChemR23, were found to be downregulated

Primary outcomes included efficacy of treatment and patient survival

Two criteria were used for the discrimination of signals from the background: i) the peak high must be higher or equal to 1000 and ii) the peaks signal-to-noise ratio given by the software must be higher or equal to 10

Betulin, a naturally occurring triterpene with anti-inflammatory and antioxidant activity, has recently been formulated into NLCs for psoriasis therapy [123, 124, 134]