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Colonic butyrate producers shape the gut microbial community by secreting various anti-microbial substances, such as cathelicidins, reuterin, and -defensin-1, and maintain gut homeostasis by releasing anti-inflammatory molecules, such as IgA, vitamin B, and microbial anti-inflammatory molecules

Moreover, taurine supplementation can also reduce the oxidative stress in the nerves and accelerate the speed of neurotransmission, and improve the intraneural blood circulation (123)

In the bulk of genomic DNA, most CpG sites are heavily methylated while CpG islands (sites of CpG clusters) in germ-line tissues and located near promoters of normal somatic cells, remain unmethylated, thus allowing gene expression to occur

Crosstalk Between NO and VEGF Pathways The mechanistic picture becomes richer when NO and VEGF pathways are considered together rather than in isolation