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The lung microbiome: a central mediator of host inflammation and metabolism in lung cancer patients

and vi) effect of topical therapies for several skin diseases by morphological analysis of the tissue [7]

Paun A, Danska JS (2015) Immuno-ecology: how the microbiome regulates tolerance and autoimmunity

Cu+ binds to the fatty acylated pyruvate dehydrogenase complex, inducing abnormal oligomerization and inactivation of the enzyme, which prevents pyruvate conversion to acetyl-CoA and disrupts metabolic flow via the tricarboxylic acid cycle (173,183)