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RACK1 and brain-derived neurotrophic factor: a homeostatic pathway that regulates alcohol addiction

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Functionally, NMDA receptors localized extrasynaptically on dendritic shafts bind extrasynaptic L-glu and mediate Ca 2+ influx upon relief of the Mg +2 block by dendrite depolarization upon backfiring of action potentials (Wu et al., 2012)