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This strategy must include measures to tackle the overlapping use of cannabis and tobacco and the resulting harm to health. The study found that cannabis was disproportionately used by younger people

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(Fleischmann et al., 1986), others have identified significant increases in UGT activity in smokers, particularly in placental tissue during pregnancy ( Overall, the presence of PAHs in cigarette smoke significantly alters drug metabolism by modifying the activity of critical biotransformation enzymes, such as CYPs and possibly UGTs