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Of these seven groups, the Firmicutes , Proteobacteria , and Verrucomicrobia phyla demonstrated a significant main effect of treatment group on relative abundance after BenjaminiHochberg correction for multiple comparisons, while Bacteroidetes and Actinobacteria demonstrated significant main effects of treatment group on relative abundance before BenjaminiHochberg correction

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The last observed value can either replace a missing weight assessment for a trial participant lost to follow up or replace weight assessments that were taken after discontinuation of the active treatment or placebo, if the participant continued to have weight assessments taken at pre-determined times while off treatment