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Ethics statement The animal study was approved by the Ethics Committee for Animal Experimentation guidelines at Zagazig Universitys College of Medicine (ZU-IACUC/3/F/244/2022)

Once translocated into systemic circulation, LPS activates toll-like receptor 4 (TLR4), triggering NF-B-mediated release of proinflammatory cytokines ( e.g ., TNF-, IL-6) and further aggravating insulin resistance and ovarian inflammation (69)

The search for this elusive substance ended in 1932 when Albert Szent-GyorgyiExit Disclaimer, a Hungarian biochemist, isolated and identified a 6-carbon carbohydrate, hexuronic acid, as the anti-scurvy factor

Effect of smoking reduction and cessation on the plasma levels of the oxidative stress biomarker glutathione--Post-hoc analysis of data from a smoking cessation trial