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J Prev Med Public Health 45(6):353 Hosseinniaee S, Jafari M, Tavili A, Zare S, Cappai G (2023) Investigating metal pollution in the food chain surrounding a lead-zinc mine (Northwestern Iran)

IGF-1 can also help decrease age-related muscle wasting (also called sarcopenia or muscle atrophy) by preserving lean muscle mass

But more common in middle-aged females

It is important to note that claims about increased energy expenditure in humans remain insufficiently evidenced at this stage, and the net glycaemic effects reflect observed trial outcomes rather than a straightforward mechanistic reduction in hepatic glucose output the concurrent glucagon receptor agonism may, in fact, influence hepatic glucose production in a complex and not fully characterised manner