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A more recent docking and MD simulation study demonstrates that in addition to the S1, cocaine can also bind in another new allosteric site formed by TMs 3, 9, 10, and 12 (Xu and Chen, 2020)

, fluoxetine (78) sertraline (79), promote remission in acute experimental autoimmune encephalomyelitis) BPC 157 affects with region specific influence the brain serotonin synthesis (-[14C]methyl-l-tryptophan autoradiographic measurements) (80), reduces the duration of immobility to a greater extent than imipramine (81)