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Beyond its anticancer and antitumor activities, curcumin has also been found beneficial in treating various diseases such as respiratory tract infections, hepatic steatosis, skin photoaging, Parkinsons disease, obesity, diabetes, HIV-associated diarrhea, and Alzheimers disease, primarily by inhibiting amyloid beta oligomer formation (230, 231)

Furthermore, in rotenone-induced PD models (an established environmental toxin linked to increased PD risk), curcumin has shown significant antidepressant activity against toxin-induced depressive behaviors (Madiha and Haider)

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6 MPO uses peroxide as a substrate via peroxidation or chlorination reaction to produce hypochloric acid and other toxic substances that can kill different types of pathogens