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As no co-crystallised ligand was present in the PDB 1GP1 entry, the co-factor glutathione was re-docked into the receptor created by Make Receptor to verify the model and ensure that the cysteinyl sulfur of glutathione was oriented to and forming an interaction with the selenocysteine

However, these serum biomarkers neither identify DILI specifically nor indicate possible DILI before the clinical occurrence of liver injury during medication treatment (Figure 3)

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