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If the ability to reduce GSSG to GSH is overwhelmed by a high burden of oxidative stress, GSSG can be exported out of cells or react with protein sulphydryl groups to prevent a major shift in the redox equilibrium [11], thereby depleting cellular GSH

Preserving muscle while losing fat is a major therapeutic goal in obesity medicine, as loss of muscle mass can worsen metabolic function and long-term outcomes

Effect on inflammatory and apoptotic gene expression RT-PCR analysis showed significant upregulation of expression of IL-1, TLR4, HMOX1, BAX , and BCL-2 in the LPS group compared to the negative control group (Figure 2)

Chapter fourteen - an overview of metabolomics data analysis: current tools and future perspectives