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This commonly produces metabolic acidosis with low potassium because lost bicarbonate makes blood too acidic while potassium drops and weakens muscles and destabilizes heart rhythm

h , Bar graph showing relative fold change (log 2 ) in top 27 ER proteins of IP samples from ER-tag cells compared to those from control-tag HEK293T cells or to whole-cell lysate from ER-tag HEK293T cells