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I Feel Tired All the Time. Do I Need a B12 Shot?: Shawn Veiseh, M.D.: Family Medicine does b12 injection cause headache Vitamin B12 deficiency can cause symptoms like headaches, fatigue, depressive mood, gastrointestinal issues, and In a 42 year old woman with chronic fatigue and a serum vitamin B12 (cobalamin) level of 275 pg mL, is intramuscular B12 injection therapy indicated? Chronic Fatigue: Can B12 Shots Make You Tired? PA Relief
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