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128 There are several treatment options for those who do not have an adequate response after four to eight weeks of antidepressant therapy: increase the dose, switch to a different antidepressant, combine antidepressants, or use another type of medication to augment the effect of the antidepressant

A practical application of the combined model would be to predict the concentration and exposure time required to cause toxicity via overwhelming GSH metabolism as a function of quinone metabolism

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Paul Conti, Trauma & Recovery (00:02:30) Sponsors (00:07:00) Defining Trauma (00:14:05) Guilt & Shame, Origins of Negative Emotions (00:21:38) Repeating Trauma, the Repetition Compulsion (00:28:23) How to Deal with Trauma & Negative Emotions/Arousal (00:37:17) Processing Trauma, Do You Always Need a Therapist