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The lower section contrasts therapeutic endpointsclearance of airway secretions, resolution of bronchospasm, and adequate cardiovascular parameterswith unreliable indicators such as pupillary dilation or isolated tachycardia

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In contrast, folate deficiency in Apolipoprotein E (ApoE)-deficient mice is reported to increase glutathione levels, possibly as a compensatory response to oxidative stress in the brain [76]