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While they serve crucial roles in immune responses and cellular signaling, they also contribute to ferroptosis

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Ferritin is an intracellular iron protein that stores and releases free iron (in ferrous form) in a controlled way

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This upregulation leads to mitochondrial fragmentation and elevated ROS generation, impairing eNOS activation

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In addition, it also helps block the deposition of fats in visceral and peripheral organs

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