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FR biology is also being exploited by the naked antibody farletuzumab, which has progressed to phase III trials

Pharmacol Res 41 : 341346 Kuratsune H, Watanabe Y, Yamaguti K, Jacobsson G, Takahashi M, Machii T, Onoe H, Onoe K, Matsumura K, Valind S, Kitani T, Lngstrm B

This suggests that hematopoietic differentiation is a continuum with no clearly defined intermediate states

Ozcan M, Esendagli G, Musdal Y, Canpinar H, Bacanli M, Anlar HG, Esendagli-Yilmaz G, Beyramzadeh M, Aksoy Y (2019) Dual actions of the antioxidant chlorophyllin, a glutathione transferase P11 inhibitor, in tumorigenesis and tumor progression