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doi: 10.1016/j.cell.2016.08.072 9 KrogsgaardMDavisMM

The reconstituted solution should be used within 24 hours when stored at or below 25C (77F) and not refrigerated or frozen

For researchers running dose-escalation studies or comparing multiple dosing regimens simultaneously, smaller vial sizes (5mg/5mg or 6mg/6mg) offer flexibilityeach subject cohort can be assigned a dedicated vial, minimizing cross-contamination risk and simplifying dose tracking

2.6 Ultra-high-performance liquid chromatographyhigh-resolution mass spectrometry analysis 2.6.1 UHPLC conditions Samples were evaluated with a Vanquish ultra-high-performance liquid chromatographyhigh-resolution mass spectrometry (UHPLC) system manufactured by Thermo Fisher Scientific, Germany, connected to an ACQUITY UPLC HSS T3 column with dimensions of 2.1 mm 100 mm and a particle size of 1.8 m