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No human dose-finding trial has been completed

205 A plant-based diet is often considered to be healthful, but not all plant-based eaters consume high amounts of whole, nutrient-dense, unprocessed foods

Unlike mitochondrial ROS, which are produced as metabolic byproducts, NOX enzymes generate ROS in a tightly regulated and deliberate manner as part of redox signaling networks (Magnani and Mattevi, 2019