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L.KrumanY.GuoZ.PenixL.et al

A healthy gut microbiome also plays a role, as gut bacteria assist in the conversion process

The insoluble amyloid crystalline assemblies induced by the SARS-CoV-2 virus not only present huge obstacles against clearance by the glymphatic system, but also accelerate and promote the self-assembly of additional insoluble A-sheet-rich, inert, stable structures that encourage sequestration of proteins, promoting loss-of-function toxicity