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The cytokines IL-12 and IL-23 play a central role in T-cell-mediated regulation, and their use as therapeutic targets has highlighted their importance to host defense and inflammatory disease [66,67,68]

[DOI] [PubMed] [Google Scholar] 48.Takahashi G, Hoshikawa K, Kan S, Akimaru R, Kodama Y, Sato T, Kakisaka K, Yamada Y

A comparative assessment of national approaches to defining the Ocean economy (Monterey, CA, USA: Final Report to the National Oceanic and Atmospheric Administration, Issue