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The symptoms of a vitamin B-12 deficiency may include: Fatigue, weakness Memory loss Depression Confusion Insomnia Shortness of breath Poor sense of balance Vision problems Diarrhoea or constipation Loss of appetite Cognitive functioning problems Beefy, red, smooth and sore tongue Sore mouth and/or bleeding gums Numbness and tingling of hands and feet Loss of hearing and tinnitus Pale, possibly yellowish pallor in light-skinned individuals

doi: 10.7554/elife.34408 41

Long-Term Value of B12 Injection Therapy B12 Injection therapy offers not only short-term health benefits but also long-term value

It is an inert vehicle, so any adverse effects are usually related to the act of injection or the medication being administered rather than the diluent