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Nearly all body Zn is intracellular, with about 50% of that in the cytoplasm, 40% in the nucleus, and 10% in cellular and organelle membranes (20)

43,50 Imerslund-Grsbeck syndrome (IGS) is a rare autosomal recessive disorder characterized by selective malabsorption of vitamin B12 in the terminal ileum, leading to systemic cobalamin deficiency