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Huntington Study Group TREND-HD Investigators

Sudden cessation or dosage reduction can trigger withdrawal symptoms as the body adjusts

Dangin M, Boirie Y, Guillet C, Beaufrere B

"Patients will suffer from the usual side-effects of extreme tiredness, irrational behaviour, mood swings, memory problems." The British National Formulary, which sets guidelines for the use of vitamin B12 in pernicious anaemia, said the practice was based on the best available evidence base