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Common side effects are typically mild and transient: Pain, redness, or swelling at the injection site (most frequent) Mild diarrhoea or gastrointestinal upset Headache or dizziness shortly after administration Itching or mild skin reactions Temporary pink/red discolouration of urine These effects usually resolve within 2448 hours without intervention

Metformin , the first-line treatment for type 2 diabetes, is associated with reduced B12 levels in approximately 1030% of long-term users

Nausea (28%), diarrhea (23%), constipation (17%), and vomiting (12%) at the 12mg dose are the most commonly reported