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Description

Cellular defenses are activated in response to insults to oxidized DNA and include four major repair mechanisms: 1 ) nucleotide excision repair (NER) and 2 ) base excision repair (BER), both of which excise bulky helix-distorting DNA lesions

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Concomitant inhibition of MDM2 and Bcl-2 protein function synergistically induce mitochondrial apoptosis in AML

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