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Glutathione Peroxidase an overview ScienceDirect Topics Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. glutathione peroxidase gsh px inhibited by iron ncbi Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme mimicking activities, and low molecular weight antioxidants The glutathione Frontiers Ferroptosis in osteoarthritis: metabolic reprogramming, immunometabolic crosstalk, and targeted intervention strategies
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